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HEMI-MANDIBULAR RECONSTRUCTION USING RIB AND PMCB WITH BIOABSORBABLE POLY(PLLA-PGA) MESH TRAY

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Á¤ÁÖÀº (  ) - À»ÁöÀÇ°ú´ëÇк´¿ø Ä¡°ú ±¸°­¾Ç¾È¸é¿Ü°ú

Abstract

°á·Ð
ÀúÀÚµîÀº ÇϾǰñÀÇ ¹ý¶û¾Æ¼¼Æ÷Á¾À¸·Î ÆíÃø ÇϾǰñ ÀýÁ¦¼úÀ» ½ÃÇàÇÑ ¿©ÀÚȯÀÚ¿¡¼­ »ýÈí¼ö
¼º Æú¸®(PUA-PGA) ¸Þ½¬¸¦ Æ®·¹ÀÌ·Î ÀÌ¿ëÇÏ¿© ÀÚ°¡¸Á»ó°ñ ¹× ´Á°ñ°ú ÇÔ²² ÇϾǰñ Àç°Ç¼ú
À» ½ÃÇàÇÑ ¹Ù ¼ö¼ú ÈÄ ¸¸Á·ÇÒ¸¸ÇÑ °á°ú¸¦ ¾ò¾ú±â¿¡ ¹®Çå°íÂû°ú ÇÔ²² º¸°íÇÏ´Â ¹ÙÀÌ´Ù.
1. ÇϾǰñÀÇ ¿¬¼Ó¼ºÀÌ »ó½ÇµÈ °æ¿ì ÀúÀÛ, ¹ßÀ½, ¿¬ÇÏÀÛ¿ëÀÇ Á¤»óÀûÀΠȸº¹ ¹× ÀûÀýÇÑ ¾È¸ð
ÀÇ ½É¹Ì¼ºÀÇ À¯Áö¿Í ÀûÀýÇÑ Ä¡Á¶°ñ ³ôÀÌÀÇ Àç°ÇÀ» ÅëÇÑ ÀÌÂ÷ÀûÀÎ º¸Ã¶¹°ÀÇ ¼öº¹À̳ª ÀΰøÄ¡
¾Æ¸Å½Ä¼ö¼úÀÌ °¡´ÉÇÒ ¼ö ÀÖµµ·Ï Àç°ÇÀÌ ÀÌ·ç¾îÁ®¾ß ÇÑ´Ù.
2. ÀÚ°¡°ñÀ» ÀÌ¿ëÇÑ Àç°Ç¹æ¹ý Áß PMCB´Â ´Ù·®ÀÇ °ñÇü¼º ÀáÀç·ÂÀ» °¡Áø ¼¼Æ÷¸¦ À̽ÄÇÒ
¼ö ÀÖ´Ù´Â Á¡°ú ÀÔÀÚÇüÅ·ΠÀÎÇØ ÀçÇ÷°üÈ­°¡ Á¶±â¿¡ ÀϾ ¼ö ÀÖ´Ù´Â ÀåÁ¡À¸·Î ÀÎÇØ
PMCB¸¦ ´ãÀ» ¼ö ÀÖ´Â ¿©·¯ Á¾·ùÀÇ tray³ª crib°ú ÇÔ²² ÇϾǰñ Àç°ÇÀ» À§ÇØ »ç¿ëµÈ´Ù.
3. ÇϾǰñ Àç°ÇÀ» À§ÇØ PMCB¿Í ÇÔ²² ÀÌ¿ëµÇ´Â trayÀÇ Á¾·ù¿¡´Â alloplastic tray, µ¿Á¾°ñ
crib, ÀÚ°¡°ñ cribÀÌ ÀÖÀ¸¸ç alloplastic tray Áß º» Áõ·Ê¿¡¼­ »ç¿ëÇÑ »ýÈí¼ö¼º Æú¸®
(PUA-PGA)¸Þ½¬ Æ®·¹ÀÌ´Â »ýü³»¿¡¼­ ºÐÇØ Èí¼öµÇ´Â Àç·á·Î¼­ ÀÌÂ÷ÀûÀÎ Á¦°Å ¼ö¼úÀÌ ÇÊ¿ä
ÇÏÁö ¾Ê°í °ñÇü¼º °úÁ¤µ¿¾È ÀûÀýÇÑ °­µµ¸¦ ºÎ¿©Çϸç, »ýü ÀûÇÕÇÑ Àç·á·Î¼­ À̹°¹ÝÀÀÀÌ ¾ø
°í, ƯÈ÷ ¼ö¼ú°úÁ¤µ¿¾È ¿ÜÇüÀ» ½±°Ô ¸¸µé ¼ö ÀÖ¾î ½É¹ÌÀûÀÎ ÇϾǰñ Àç°Ç¿¡ À¯¿ëÇϸ®¶ó »ç·á
µÇ´Â ¹ÙÀÌ´Ù.

Loss of mandibular continuity can occur secondary to trauma, infection, or tumor
resection. The basic goal of mandibular reconstruction is to restore bony continuity,
osseous bulk, acceptable facial form.
During the mandibular reconstruction is considered, surgical choices of using
autogenous bone are divided into non-vascularized cortico-cancellous bone block graft,
vascularized transfer of a cortico-cancellous bone block, and particulate marrow and
cancellous bone (PMCB) graft. The PMCB has been successfully used for the
reconstruction of mandibular osseous defect since introduced by Boyne, et al. This graft
transplants a great density of osteocompetent cells, and promotes an early
revascularization with vascular ingrowth with their particulate nature. However, because
of their particulate nature, require tray or crib for containing PMCB. The Titanium
mesh and Dacron-urethane trays have been used widely for this purpose, and allogenic
mandible or rib, ilium have been also used.
Recently, bioabsorbable polymer material is used to surgeon for treatment of
craniofacial fracture and congenital anomaly of craniofacial skeleton in the form of plate,
mesh and screw. In different natures to metal material, secondary operation is
unnecessary due to biological degradation and resorption in the body with timing, and it
can give adequate strength during the bone healing period. and it can be contoured
easily during the operation. Especially, in pediatric applications, it can diminish the
possibility of growth disturbance and back-scattering effects diminished when radiation
therapy applied. Recently, the literature was reported for jaw reconstruction with PMCB
and bioabsorbable polymer tray with animal study.
In this case, 18-years old woman, who was diagnosed as ameloblastoma, was shown
hemimandibular osseous defects. We performed secondary reconstruction using PMCB
from posterior ilium, and rib bone with bioabsorbable poly(PLLA-PGA) mesh as a tray,
and some favorable results were obtained and we report it preliminarily, with literature
reviews.

Å°¿öµå

mandible reconstruction; PMCB; PLLA-PCA polymer;

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